Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHF8PHD finger protein 8. (1060 aa)    
Predicted Functional Partners:
H3-4
Histone H3; Belongs to the histone H3 family.
    
 0.826
SUV39H1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 0.790
TOPBP1
DNA topoisomerase II binding protein 1.
    
 
 0.766
ZNF711
Zinc finger protein 711.
   
 0.761
CCNA2
Cyclin A2; Belongs to the cyclin family.
    
 0.743
ARID5B
AT-rich interaction domain 5B.
    
 0.722
G8F5U3_MACFA
Histone H3; Belongs to the histone H3 family.
    
 0.700
NCAPG2
Non-SMC condensin II complex subunit G2.
   
 
 0.676
NCAPD3
Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
   
 
 0.674
RARA
Retinoic acid receptor alpha.
    
 
 0.604
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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