Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSMFAP00000001055Ion_trans domain-containing protein. (199 aa)    
Predicted Functional Partners:
CATSPER3
Cation channel sperm associated 3.
  
 
 0.887
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.857
CATSPER4
Cation channel sperm associated 4.
  
 0.854
CATSPER1
Cation channel sperm associated 1.
   
 0.854
ENSMFAP00000037359
Ion_trans domain-containing protein.
 
     0.852
CATSPERD
Cation channel sperm-associated protein subunit delta; Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane; Belongs to the CATSPERD family.
  
 0.846
EFCAB9
EF-hand calcium binding domain 9.
  
 
 
 0.840
CATSPERE
Catsper channel auxiliary subunit epsilon.
  
 
 0.801
CATSPERB
Cation channel sperm associated auxiliary subunit beta.
  
 
 0.773
CATSPERG
Cation channel sperm-associated protein subunit gamma; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
  
 
 0.759
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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