STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HINT1HIT domain-containing protein. (126 aa)    
Predicted Functional Partners:
CTSA
Carboxypeptidase; Belongs to the peptidase S10 family.
      
 0.916
CES1
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.898
LOC102128556
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.897
LOC102127617
Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.853
TAF1D
TATA-box binding protein associated factor, RNA polymerase I subunit D.
    
 0.705
GUK1
Guanylate kinase 1.
  
 
 0.703
TAF1A
Uncharacterized protein.
    
 0.635
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
     
 0.632
RPL35A
60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
   
  
 0.602
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.584
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.