Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DTX3Deltex E3 ubiquitin ligase 3. (350 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
 0.723
NOTCH4
Notch receptor 4.
    
 0.695
NOTCH3
Notch receptor 3.
    
 0.684
NOTCH2
Notch receptor 2.
    
 0.681
VGLL1
Vestigial like family member 1.
      
 0.568
ANKRD37
Ankyrin repeat domain 37.
    
 0.555
DTX1
Deltex E3 ubiquitin ligase 1.
  
   
0.440
RNF130
Ring finger protein 130.
   
 0.428
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.421
RNF150
Ring finger protein 150.
   
 0.421
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.