Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCAF8DDB1 and CUL4 associated factor 8. (597 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.976
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.971
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.970
DCAF7
DDB1 and CUL4 associated factor 7.
    
 0.869
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.840
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
    
 0.838
DCAF5
DDB1 and CUL4 associated factor 5.
     
0.827
DCAF17
DDB1 and CUL4 associated factor 17.
     
 0.824
DDB2
Damage specific DNA binding protein 2.
    
 0.821
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.821
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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