Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMX1Thioredoxin related transmembrane protein 1. (280 aa)    
Predicted Functional Partners:
TMX2
Thioredoxin-related transmembrane protein 2.
    
 
 0.833
AGR3
Anterior gradient 3, protein disulphide isomerase family member.
      
 0.727
ERP44
Thioredoxin domain-containing protein.
   
  
 0.725
NOXO1
NADPH oxidase organizer 1.
    
 
 0.720
TMX3
Thioredoxin related transmembrane protein 3.
   
 
0.712
NOXA1
NADPH oxidase activator 1.
      
 0.710
CANX
Calnexin.
   
 0.654
ERP27
Endoplasmic reticulum protein 27.
   
  
 0.635
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase.
   
 
 0.616
AGR2
Anterior gradient 2, protein disulphide isomerase family member.
    
 
 0.581
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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