Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBCKTBC1 domain containing kinase. (893 aa)    
Predicted Functional Partners:
C12orf4
Chromosome 12 open reading frame 4.
    
 
 0.914
IL6R
Interleukin 6 receptor.
    
 
 0.826
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
   
 
 0.718
RBPMS
RNA binding protein, mRNA processing factor.
    
   0.629
TCP10L
Testis cDNA clone: QtsA-10687, similar to human t-complex 10 (mouse)-like (TCP10L).
    
   0.609
NME6
Nucleoside diphosphate kinase.
   
  
 0.579
CNPY2
Canopy FGF signaling regulator 2.
      
 0.564
POLR2E
Uncharacterized protein.
      
 0.530
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.493
MOSPD3
Motile sperm domain containing 3.
      
 0.480
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (30%) [HD]