Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTRH2Peptidyl-tRNA hydrolase 2. (180 aa)    
Predicted Functional Partners:
ATP6V0A2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
   0.721
USP30
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.697
COA5
Cytochrome c oxidase assembly factor 5.
   
 
 0.695
ERBIN
Erbb2 interacting protein.
      
 0.690
COX15
Cytochrome c oxidase assembly homolog COX15.
     
 0.686
TLE5
TLE_N domain-containing protein.
    
 
 0.652
BPTF
Bromodomain PHD finger transcription factor.
      
 0.635
SCO1
SCO cytochrome c oxidase assembly protein 1.
     
 0.612
LOC102135146
CHCH domain-containing protein.
   
 
 0.606
BTBD8
BTB domain containing 8.
      
 0.585
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (28%) [HD]