STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP1E3 ubiquitin-protein ligase. (922 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
   
  0.872
ARRDC1
Arrestin domain containing 1.
    
 
 0.856
DVL2
Dishevelled segment polarity protein 2.
    
 0.838
KLF5
Kruppel like factor 5.
    
 0.837
EGFR
Receptor protein-tyrosine kinase.
    
 0.829
SPART
Spartin.
    
 
 0.821
SMAD7
Mothers against decapentaplegic homolog.
    
 0.819
WBP2
WW domain binding protein 2.
    
 
 0.810
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.810
ARRDC3
Arrestin domain containing 3.
    
 
 0.801
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.