node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COPS2 | COPS4 | ENSMFAP00000033926 | ENSMFAP00000027787 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | 0.999 |
COPS2 | COPS8 | ENSMFAP00000033926 | ENSMFAP00000024811 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome subunit 8. | 0.999 |
COPS2 | CUL4A | ENSMFAP00000033926 | ENSMFAP00000024748 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | Cullin 4A; Belongs to the cullin family. | 0.938 |
COPS2 | CUL4B | ENSMFAP00000033926 | ENSMFAP00000030412 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | Cullin 4B; Belongs to the cullin family. | 0.931 |
COPS2 | DCAF11 | ENSMFAP00000033926 | ENSMFAP00000011624 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family. | 0.793 |
COPS2 | DDA1 | ENSMFAP00000033926 | ENSMFAP00000043888 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | DET1 and DDB1 associated 1. | 0.562 |
COPS2 | DDB1 | ENSMFAP00000033926 | ENSMFAP00000030117 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | Damage specific DNA binding protein 1. | 0.860 |
COPS2 | WDTC1 | ENSMFAP00000033926 | ENSMFAP00000001176 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | WD and tetratricopeptide repeats 1. | 0.704 |
COPS4 | COPS2 | ENSMFAP00000027787 | ENSMFAP00000033926 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | 0.999 |
COPS4 | COPS8 | ENSMFAP00000027787 | ENSMFAP00000024811 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | COP9 signalosome subunit 8. | 0.999 |
COPS4 | CUL4A | ENSMFAP00000027787 | ENSMFAP00000024748 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | Cullin 4A; Belongs to the cullin family. | 0.934 |
COPS4 | CUL4B | ENSMFAP00000027787 | ENSMFAP00000030412 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | Cullin 4B; Belongs to the cullin family. | 0.919 |
COPS4 | DCAF11 | ENSMFAP00000027787 | ENSMFAP00000011624 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family. | 0.704 |
COPS4 | DDA1 | ENSMFAP00000027787 | ENSMFAP00000043888 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | DET1 and DDB1 associated 1. | 0.571 |
COPS4 | DDB1 | ENSMFAP00000027787 | ENSMFAP00000030117 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | Damage specific DNA binding protein 1. | 0.903 |
COPS4 | WDTC1 | ENSMFAP00000027787 | ENSMFAP00000001176 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | WD and tetratricopeptide repeats 1. | 0.792 |
COPS8 | COPS2 | ENSMFAP00000024811 | ENSMFAP00000033926 | COP9 signalosome subunit 8. | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | 0.999 |
COPS8 | COPS4 | ENSMFAP00000024811 | ENSMFAP00000027787 | COP9 signalosome subunit 8. | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | 0.999 |
COPS8 | CUL4A | ENSMFAP00000024811 | ENSMFAP00000024748 | COP9 signalosome subunit 8. | Cullin 4A; Belongs to the cullin family. | 0.904 |
COPS8 | CUL4B | ENSMFAP00000024811 | ENSMFAP00000030412 | COP9 signalosome subunit 8. | Cullin 4B; Belongs to the cullin family. | 0.903 |