Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM46Tripartite motif containing 46. (759 aa)    
Predicted Functional Partners:
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 
 0.655
THBS3
Thrombospondin 3.
    
 0.639
MTX1
Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family.
      
 0.631
MAP7D3
MAP7 domain containing 3.
    
 0.609
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
    
 
 0.600
MAP7D1
MAP7 domain containing 1.
    
 0.583
MUC1
Mucin 1, cell surface associated.
    
 0.547
ERICH3
Glutamate rich 3.
    
 0.543
PLBD1
Phospholipase B-like; Putative phospholipase.
      
 0.528
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 
 0.522
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.