Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XPNPEP2X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family. (674 aa)    
Predicted Functional Partners:
MEP1B
Meprin A subunit.
   
 
 0.943
MEP1A
Meprin A subunit.
   
 
 0.937
ACE2
Angiotensin-converting enzyme.
   
 
 0.922
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
   
 
 0.921
PRCP
Prolylcarboxypeptidase.
   
 
 0.918
MME
Membrane metalloendopeptidase.
   
 
 0.917
MOGAT3
Monoacylglycerol O-acyltransferase 3.
   
  
 0.723
SLC2A2
Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
 0.723
ATP1B1
Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).
   
  
 0.700
EVA1B
Eva-1 homolog B.
      
 0.689
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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