Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIF2B3Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. (452 aa)    
Predicted Functional Partners:
EIF2B2
Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2B4
Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2B5
Eukaryotic translation initiation factor 2B subunit epsilon.
   
0.999
EIF2B1
Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.964
OPN3
Opsin 3; Belongs to the G-protein coupled receptor 1 family.
    
   0.804
ENSMFAP00000006481
eIF2B_5 domain-containing protein.
   
 0.796
ENSMFAP00000021728
eIF2B_5 domain-containing protein.
   
 0.796
EIF2S2
Eukaryotic translation initiation factor 2 subunit beta.
   
 0.796
ENSMFAP00000045139
eIF2B_5 domain-containing protein.
   
 0.796
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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