Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC28Leucine rich repeat containing 28. (367 aa)    
Predicted Functional Partners:
KAZN
Kazrin, periplakin interacting protein.
      
 0.610
NYX
Nyctalopin.
  
 
 0.610
SUPT3H
SPT3 homolog, SAGA and STAGA complex component.
    
 
 0.607
SLC12A8
Solute carrier family 12 member 8.
     
 0.587
NSMAF
Uncharacterized protein.
      
 0.585
NSG1
Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatoden [...]
      
 0.584
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 0.562
RGS20
Regulator of G protein signaling 20.
      
 0.527
PRDM2
PR/SET domain 2.
     
 0.521
VWA7
Von Willebrand factor A domain containing 7.
    
 0.480
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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