Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRY2Protein sprouty homolog 2; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. (338 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.993
CBLB
Cbl proto-oncogene B.
    
 0.947
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.940
GRB2
Growth factor receptor-binding protein 2.
    
 0.924
HBEGF
Heparin binding EGF like growth factor.
   
 
 0.773
EREG
Epiregulin.
     
 0.766
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.759
SPRY1
Sprouty RTK signaling antagonist 1.
   
  0.754
ZDHHC17
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.733
AREG
Amphiregulin.
     
 0.727
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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