Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HELQHelicase, POLQ like. (1101 aa)    
Predicted Functional Partners:
POLN
DNA polymerase nu.
 
  
 
 0.855
FANCD2
Uncharacterized protein.
   
 0.834
MMS22L
MMS22 like, DNA repair protein.
   
  
 0.826
FANCM
FA complementation group M.
   
 
 0.819
ENSMFAP00000045057
Uncharacterized protein.
   
 0.778
FANCL
FA complementation group L.
     
 0.703
EXO1
Exonuclease 1.
  
 
 0.682
MUS81
MUS81 structure-specific endonuclease subunit.
   
 
 0.679
FAAP24
PND domain-containing protein.
     
 0.670
FANCI
FA complementation group I.
   
 0.669
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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