DHRS11 protein (Macaca fascicularis) - STRING interaction network

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DHRS11

Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)

Predicted Functional Partners:

CYP17A1

0.961

CYP11B1

0.931

LOC102137301

0.931

HSD11B1

0.919

HSD11B1L

0.912

HSD17B2

0.801

HSD17B4

0.715

HSD17B1

0.690

HSD11B2

0.646

PIGW

0.635

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11B1	CYP17A1	ENSMFAP00000013397	ENSMFAP00000004698	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	0.946
CYP11B1	DHRS11	ENSMFAP00000013397	ENSMFAP00000001303	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.931
CYP11B1	HSD11B1	ENSMFAP00000013397	ENSMFAP00000007427	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta dehydrogenase 1.	0.931
CYP11B1	HSD11B1L	ENSMFAP00000013397	ENSMFAP00000027179	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta-dehydrogenase 1-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.917
CYP11B1	HSD11B2	ENSMFAP00000013397	ENSMFAP00000040692	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta dehydrogenase 2.	0.941
CYP11B1	HSD17B1	ENSMFAP00000013397	ENSMFAP00000014863	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.559
CYP11B1	HSD17B2	ENSMFAP00000013397	ENSMFAP00000005858	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	17-beta hydroxysteroid dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.922
CYP11B1	LOC102137301	ENSMFAP00000013397	ENSMFAP00000014370	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.901
CYP17A1	CYP11B1	ENSMFAP00000004698	ENSMFAP00000013397	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	0.946
CYP17A1	DHRS11	ENSMFAP00000004698	ENSMFAP00000001303	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.961
CYP17A1	HSD11B1	ENSMFAP00000004698	ENSMFAP00000007427	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Hydroxysteroid 11-beta dehydrogenase 1.	0.952
CYP17A1	HSD11B1L	ENSMFAP00000004698	ENSMFAP00000027179	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Hydroxysteroid 11-beta-dehydrogenase 1-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.919
CYP17A1	HSD11B2	ENSMFAP00000004698	ENSMFAP00000040692	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Hydroxysteroid 11-beta dehydrogenase 2.	0.632
CYP17A1	HSD17B1	ENSMFAP00000004698	ENSMFAP00000014863	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.612
CYP17A1	HSD17B2	ENSMFAP00000004698	ENSMFAP00000005858	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	17-beta hydroxysteroid dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.939
CYP17A1	LOC102137301	ENSMFAP00000004698	ENSMFAP00000014370	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.946
DHRS11	CYP11B1	ENSMFAP00000001303	ENSMFAP00000013397	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family.	0.931
DHRS11	CYP17A1	ENSMFAP00000001303	ENSMFAP00000004698	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...]	0.961
DHRS11	HSD11B1	ENSMFAP00000001303	ENSMFAP00000007427	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 11-beta dehydrogenase 1.	0.919
DHRS11	HSD11B1L	ENSMFAP00000001303	ENSMFAP00000027179	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 11-beta-dehydrogenase 1-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.912

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