Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BMP1Metalloendopeptidase. (986 aa)    
Predicted Functional Partners:
TLL2
Metalloendopeptidase.
   
  0.943
PCOLCE
Procollagen C-endopeptidase enhancer.
   
 0.917
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.907
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
    
 
 0.792
COL3A1
Collagen type III alpha 1 chain.
   
 0.721
IGSF21
Immunoglobin superfamily member 21.
      
 0.697
COL1A1
Collagen type I alpha 1 chain.
   
 0.669
GDF11
Growth differentiation factor 11.
    
 
 0.647
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
   
 0.634
COL5A2
Collagen type V alpha 2 chain.
   
 0.625
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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