| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACO1 | ACO2 | ENSMFAP00000003967 | ENSMFAP00000024254 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Aconitase 2. | 0.926 |
| ACO1 | CS | ENSMFAP00000003967 | ENSMFAP00000004989 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.996 |
| ACO1 | ENSMFAP00000018367 | ENSMFAP00000003967 | ENSMFAP00000018367 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Uncharacterized protein. | 0.597 |
| ACO1 | IDH1 | ENSMFAP00000003967 | ENSMFAP00000037246 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.989 |
| ACO1 | IDH2 | ENSMFAP00000003967 | ENSMFAP00000002582 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.990 |
| ACO1 | IDH3A | ENSMFAP00000003967 | ENSMFAP00000001379 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.959 |
| ACO1 | IDH3B | ENSMFAP00000003967 | ENSMFAP00000015864 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.959 |
| ACO1 | IDH3G | ENSMFAP00000003967 | ENSMFAP00000039635 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.957 |
| ACO1 | OGDH | ENSMFAP00000003967 | ENSMFAP00000029899 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...] | 0.646 |
| ACO1 | OGDHL | ENSMFAP00000003967 | ENSMFAP00000017275 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Oxoglutarate dehydrogenase like. | 0.581 |
| ACO2 | ACO1 | ENSMFAP00000024254 | ENSMFAP00000003967 | Aconitase 2. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.926 |
| ACO2 | CS | ENSMFAP00000024254 | ENSMFAP00000004989 | Aconitase 2. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.998 |
| ACO2 | ENSMFAP00000018367 | ENSMFAP00000024254 | ENSMFAP00000018367 | Aconitase 2. | Uncharacterized protein. | 0.817 |
| ACO2 | IDH1 | ENSMFAP00000024254 | ENSMFAP00000037246 | Aconitase 2. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.984 |
| ACO2 | IDH2 | ENSMFAP00000024254 | ENSMFAP00000002582 | Aconitase 2. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.986 |
| ACO2 | IDH3A | ENSMFAP00000024254 | ENSMFAP00000001379 | Aconitase 2. | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.992 |
| ACO2 | IDH3B | ENSMFAP00000024254 | ENSMFAP00000015864 | Aconitase 2. | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.988 |
| ACO2 | IDH3G | ENSMFAP00000024254 | ENSMFAP00000039635 | Aconitase 2. | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | 0.980 |
| ACO2 | OGDH | ENSMFAP00000024254 | ENSMFAP00000029899 | Aconitase 2. | 2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...] | 0.918 |
| ACO2 | OGDHL | ENSMFAP00000024254 | ENSMFAP00000017275 | Aconitase 2. | Oxoglutarate dehydrogenase like. | 0.892 |
