Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MRC1Mannose receptor C-type 1. (1456 aa)    
Predicted Functional Partners:
MRC2
Mannose receptor C type 2.
     
0.952
PLA2R1
Phospholipase A2 receptor 1.
     
0.904
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
   
 0.739
FCGR1A
Uncharacterized protein.
   
 
 0.726
CX3CR1
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.720
FIBCD1
Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non- acetylated counterparts. Can facilitate the endocytosis of acetylated components (By similarity).
   
 0.708
CD163
CD163 molecule.
   
 0.705
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
   
 0.696
F13A1
Coagulation factor XIII A chain.
   
 0.682
ADGRE1
Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family.
   
 0.680
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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