Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIF1BKinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1823 aa)    
Predicted Functional Partners:
KIF1A
Kinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
  
 
0.994
KIF1C
Kinesin family member 1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
0.985
PRC1
Protein regulator of cytokinesis 1.
   
 0.768
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
  
 0.759
HOOK3
Hook microtubule tethering protein 3.
   
 0.755
YWHAH
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.755
YWHAB
14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]
    
   0.751
USH1C
USH1 protein network component harmonin.
    
 
 0.724
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
 
 0.719
CEP290
Centrosomal protein 290.
   
 0.704
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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