Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSMFAP00000001598SUI1 domain-containing protein. (115 aa)    
Predicted Functional Partners:
EIF1B
Eukaryotic translation initiation factor 1b; Probably involved in translation.
   
   0.943
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.920
UBB
Uncharacterized protein.
   
   0.804
RPS6
40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
   
 
 0.775
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
   
 
 0.769
EIF1AX
Eukaryotic translation initiation factor 1A X-linked.
   
 
 0.766
RACK1
Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Binds to and stabilizes activated protein kinase C (PKC), increasing PKC- mediated phosphorylation. May recruit activated PKC to the ribosome, leading to phosphorylation of EIF6. Inhibits the activity of SRC kinases including SRC, LCK and YES1. Inhibits [...]
   
 
 0.760
ENSMFAP00000038756
Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.735
RPS14
Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.735
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 
 0.730
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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