Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)    
Predicted Functional Partners:
PLXNC1
Plexin C1.
    
 0.999
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.957
PLXND1
Uncharacterized protein.
    
 0.783
FAM185A
Family with sequence similarity 185 member A.
    
   0.734
PCBP4
Poly(rC) binding protein 4.
    
   0.734
PLXNA1
Plexin A1.
    
 0.731
PLXNA4
Plexin A4.
    
 0.725
PLXNA2
Plexin A2.
    
 0.708
PLXNA3
Plexin A3.
    
 0.697
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
    
 0.662
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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