STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOGMyelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity). Belongs to the immunoglobulin superfamily. BTN/MOG family. (318 aa)    
Predicted Functional Partners:
MBP
Myelin basic protein.
   
  
 0.880
MOBP
Myelin-associated oligodendrocyte basic protein.
   
  
 0.809
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
    
 0.774
MAG
Myelin associated glycoprotein.
   
 
 0.724
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.699
CDSN
Corneodesmosin.
  
   
 0.669
PLP1
Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity); Belongs to the myelin proteolipid protein family.
   
  
 0.648
ZFP57
ZFP57 zinc finger protein.
   
 0.642
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase.
   
  
 0.629
COL11A2
Collagen type XI alpha 2 chain.
    
 
 0.608
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.