| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DAXX | DNMT1 | ENSMFAP00000038776 | ENSMFAP00000013116 | Death domain associated protein. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.852 |
| DAXX | TP53 | ENSMFAP00000038776 | ENSMFAP00000038526 | Death domain associated protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.994 |
| DAXX | USP40 | ENSMFAP00000038776 | ENSMFAP00000001670 | Death domain associated protein. | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.778 |
| DNMT1 | DAXX | ENSMFAP00000013116 | ENSMFAP00000038776 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Death domain associated protein. | 0.852 |
| DNMT1 | TP53 | ENSMFAP00000013116 | ENSMFAP00000038526 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.835 |
| DNMT1 | UBB | ENSMFAP00000013116 | ENSMFAP00000040895 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Uncharacterized protein. | 0.784 |
| DNMT1 | UBC | ENSMFAP00000013116 | ENSMFAP00000010479 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Ubiquitin C. | 0.726 |
| DNMT1 | USP40 | ENSMFAP00000013116 | ENSMFAP00000001670 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.640 |
| GMPS | TP53 | ENSMFAP00000044169 | ENSMFAP00000038526 | Guanine monophosphate synthase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.606 |
| GMPS | USP40 | ENSMFAP00000044169 | ENSMFAP00000001670 | Guanine monophosphate synthase. | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.735 |
| TP53 | DAXX | ENSMFAP00000038526 | ENSMFAP00000038776 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Death domain associated protein. | 0.994 |
| TP53 | DNMT1 | ENSMFAP00000038526 | ENSMFAP00000013116 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.835 |
| TP53 | GMPS | ENSMFAP00000038526 | ENSMFAP00000044169 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Guanine monophosphate synthase. | 0.606 |
| TP53 | UBB | ENSMFAP00000038526 | ENSMFAP00000040895 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Uncharacterized protein. | 0.888 |
| TP53 | UBC | ENSMFAP00000038526 | ENSMFAP00000010479 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Ubiquitin C. | 0.822 |
| TP53 | USP40 | ENSMFAP00000038526 | ENSMFAP00000001670 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.707 |
| TRAF4 | USP40 | ENSMFAP00000031511 | ENSMFAP00000001670 | TNF receptor-associated factor. | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.659 |
| TRIP12 | UBB | ENSMFAP00000030766 | ENSMFAP00000040895 | Thyroid hormone receptor interactor 12. | Uncharacterized protein. | 0.870 |
| TRIP12 | UBC | ENSMFAP00000030766 | ENSMFAP00000010479 | Thyroid hormone receptor interactor 12. | Ubiquitin C. | 0.854 |
| TRIP12 | USP40 | ENSMFAP00000030766 | ENSMFAP00000001670 | Thyroid hormone receptor interactor 12. | Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. | 0.850 |