STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)    
Predicted Functional Partners:
KCNMA1
Potassium calcium-activated channel subfamily M alpha 1.
     
 0.958
KCNN4
Potassium calcium-activated channel subfamily N member 4.
  
  
0.940
KCNU1
Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina (By similarity); Belongs to the potassium channel fa [...]
     
 0.924
KCNN2
Potassium calcium-activated channel subfamily N member 2.
  
  
0.920
KCNMB4
Potassium calcium-activated channel subfamily M regulatory beta subunit 4.
     
 0.916
KCNMB1
Potassium calcium-activated channel subfamily M regulatory beta subunit 1.
     
 0.915
KCNMB2
KcnmB2_inactiv domain-containing protein.
     
 0.915
KCNN3
Potassium calcium-activated channel subfamily N member 3.
  
  
 
0.914
KCNMB3
Potassium calcium-activated channel subfamily M regulatory beta subunit 3.
     
 0.911
PRKCG
Protein kinase C gamma type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing p [...]
   
 
 0.908
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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