Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1011 aa)    
Predicted Functional Partners:
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
   
0.999
KCNJ3
Potassium voltage-gated channel subfamily J member 3.
   
 0.969
KCNJ5
Potassium voltage-gated channel subfamily J member 5.
   
 0.959
KCNJ6
Potassium voltage-gated channel subfamily J member 6.
   
 0.957
KCNJ9
Potassium voltage-gated channel subfamily J member 9.
   
 0.951
GNAO1
G protein subunit alpha o1.
   
 0.943
GNAI1
G protein subunit alpha i1.
   
 0.938
GNAI3
G protein subunit alpha i3.
   
 0.938
GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily.
   
 0.935
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
    
 0.933
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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