Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AQP12BAquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (307 aa)    
Predicted Functional Partners:
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.850
AQP1
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.830
AQP8
Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.822
AQP10
Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.818
MIP
Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.729
AVP
Arginine vasopressin; Belongs to the vasopressin/oxytocin family.
      
 0.713
AQP7
Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (By similarity). The channel is also permeable to urea (By similarity). Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By simi [...]
     
 0.702
AQP3
Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.677
AQP9
Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.676
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.659
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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