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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQP12BAquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (307 aa)    
Predicted Functional Partners:
AQP9
Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.864
AQP8
Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.814
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.794
AQP10
Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.783
AQP1
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.776
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.752
MIP
Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.689
AQP7
Aquaporin-7; Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (By similarity). The channel is also permeable to urea (By similarity). Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By simi [...]
     
 0.659
SENP1
ULP_PROTEASE domain-containing protein.
    
 0.640
SENP2
SUMO specific peptidase 2.
    
 0.640
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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