| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSMFAP00000001720 | PSMC2 | ENSMFAP00000001720 | ENSMFAP00000030729 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.986 |
| ENSMFAP00000001720 | PSMC4 | ENSMFAP00000001720 | ENSMFAP00000036504 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 0.979 |
| ENSMFAP00000001720 | PSMC6 | ENSMFAP00000001720 | ENSMFAP00000031722 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. | 0.978 |
| ENSMFAP00000001720 | PSMD11 | ENSMFAP00000001720 | ENSMFAP00000042080 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 11. | 0.974 |
| ENSMFAP00000001720 | PSMD12 | ENSMFAP00000001720 | ENSMFAP00000019402 | AAA domain-containing protein; Belongs to the AAA ATPase family. | PCI domain-containing protein. | 0.988 |
| ENSMFAP00000001720 | PSMD13 | ENSMFAP00000001720 | ENSMFAP00000018426 | AAA domain-containing protein; Belongs to the AAA ATPase family. | PCI domain-containing protein. | 0.981 |
| ENSMFAP00000001720 | PSMD14 | ENSMFAP00000001720 | ENSMFAP00000005145 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome regulatory subunit N11. | 0.986 |
| ENSMFAP00000001720 | PSMD2 | ENSMFAP00000001720 | ENSMFAP00000037682 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.987 |
| ENSMFAP00000001720 | PSMD4 | ENSMFAP00000001720 | ENSMFAP00000045865 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 4. | 0.987 |
| ENSMFAP00000001720 | PSMD6 | ENSMFAP00000001720 | ENSMFAP00000003087 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 6. | 0.984 |
| PSMC2 | ENSMFAP00000001720 | ENSMFAP00000030729 | ENSMFAP00000001720 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.986 |
| PSMC2 | PSMC4 | ENSMFAP00000030729 | ENSMFAP00000036504 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 0.999 |
| PSMC2 | PSMC6 | ENSMFAP00000030729 | ENSMFAP00000031722 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. | 0.998 |
| PSMC2 | PSMD11 | ENSMFAP00000030729 | ENSMFAP00000042080 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | Proteasome 26S subunit, non-ATPase 11. | 0.999 |
| PSMC2 | PSMD12 | ENSMFAP00000030729 | ENSMFAP00000019402 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | PCI domain-containing protein. | 0.999 |
| PSMC2 | PSMD13 | ENSMFAP00000030729 | ENSMFAP00000018426 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | PCI domain-containing protein. | 0.999 |
| PSMC2 | PSMD14 | ENSMFAP00000030729 | ENSMFAP00000005145 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 26S proteasome regulatory subunit N11. | 0.999 |
| PSMC2 | PSMD2 | ENSMFAP00000030729 | ENSMFAP00000037682 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
| PSMC2 | PSMD4 | ENSMFAP00000030729 | ENSMFAP00000045865 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | Proteasome 26S subunit, non-ATPase 4. | 0.998 |
| PSMC2 | PSMD6 | ENSMFAP00000030729 | ENSMFAP00000003087 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | Proteasome 26S subunit, non-ATPase 6. | 0.999 |