Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSPT2G1 to S phase transition 2. (624 aa)    
Predicted Functional Partners:
ENSMFAP00000020606
eRF1_1 domain-containing protein.
   
 0.915
ETF1
eRF1_1 domain-containing protein.
   
 0.915
GSPT1
G1 to S phase transition 1.
  
  
 
0.900
UPF1
UPF1 RNA helicase and ATPase.
    
 0.871
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2.
 
  
   0.855
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.827
EPRS1
Glutamyl-prolyl-tRNA synthetase.
   
  0.810
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1.
 
  
   0.784
ZGRF1
Zinc finger GRF-type containing 1.
    
 0.751
ENSMFAP00000009958
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.735
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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