Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLITRK1SLIT and NTRK like family member 1. (696 aa)    
Predicted Functional Partners:
PTPRS
Protein tyrosine phosphatase receptor type S.
    
 0.970
KCNF1
Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family.
   
 0.943
OPCML
Opioid binding protein/cell adhesion molecule like.
   
 0.941
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3.
    
 
 0.932
KCNH3
Potassium voltage-gated channel subfamily H member 3.
      
 0.931
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
 
 0.929
GABRA5
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.902
PTPRD
Protein tyrosine phosphatase receptor type D.
    
 0.865
NTRK2
Tyrosine-protein kinase receptor.
   
 0.822
SCN1A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.791
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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