Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MACF1Microtubule actin crosslinking factor 1. (7594 aa)    
Predicted Functional Partners:
PLEC
Plectin.
    
 0.938
DST
Dystonin.
   
   0.885
JUP
Junction plakoglobin.
   
 0.861
MAPRE1
Uncharacterized protein.
    
 
 0.818
COL17A1
Collagen type XVII alpha 1 chain.
   
 0.741
ITGB4
Integrin beta.
   
 0.737
TTI1
TELO2 interacting protein 1.
    
   0.715
DSP
Desmoplakin.
    
 0.702
PKP2
Plakophilin 2.
   
 0.671
PKP1
Plakophilin 1.
   
 0.669
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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