Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CAPNS1-2Uncharacterized protein. (202 aa)    
Predicted Functional Partners:
CAPN1
Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; Belongs to the peptidase C2 family.
   
 0.891
CAPN2
Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs; Belongs to the peptidase C2 family.
   
 0.845
CAST
Calpastatin.
   
 0.836
CAPN8
Calpain 8; Belongs to the peptidase C2 family.
 
 
 0.803
CAPN7
Calpain 7; Belongs to the peptidase C2 family.
   
 0.797
CAPN5
Calpain 5; Belongs to the peptidase C2 family.
 
 
 0.762
CAPN14
Calpain 14; Belongs to the peptidase C2 family.
   
 0.746
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
    0.742
CAPN13
Calpain 13; Belongs to the peptidase C2 family.
   
 0.723
CAPN6
Calpain 6; Belongs to the peptidase C2 family.
   
 0.718
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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