Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LIPGLipase G, endothelial type. (500 aa)    
Predicted Functional Partners:
LIPF
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.946
MGLL
Monoglyceride lipase.
     
 0.925
PNPLA3
Patatin like phospholipase domain containing 3.
     
 0.924
PNPLA2
Patatin like phospholipase domain containing 2.
     
 0.921
CEL
Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family.
   
 0.916
PNLIPRP2
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
0.916
PNLIPRP1
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
0.915
PNLIPRP3
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
0.913
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
  
  
0.904
LIPC
Lipase C, hepatic type.
     
0.903
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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