Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL6Kelch like family member 6. (619 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.862
RC3H2
Ring finger and CCCH-type domains 2.
   
 
 0.830
ICOS
Inducible T cell costimulator.
   
  
 0.700
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
      
 0.692
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
   
  
 0.627
LCP1
Lymphocyte cytosolic protein 1.
   
  
 0.611
EPHB4
EPH receptor B4.
    
 0.601
NUDCD3
NudC domain containing 3.
   
 
 0.598
KLHDC2
Kelch domain containing 2.
      
 0.591
ENG
Endoglin.
      
 0.585
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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