Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC27Coiled-coil domain containing 27. (638 aa)    
Predicted Functional Partners:
MYLK
Myosin light chain kinase.
    
   0.903
CC2D1B
Coiled-coil and C2 domain containing 1B.
    
   0.903
CC2D1A
Coiled-coil and C2 domain containing 1A.
    
   0.692
LYPD4
LY6/PLAUR domain containing 4.
  
   
 0.641
KCTD10
Potassium channel tetramerization domain containing 10.
      
 0.614
TTN
Titin.
    
   0.610
SPEGNB
SPEG neighbor.
    
   0.610
TRIP11
Thyroid hormone receptor interactor 11.
      
 0.604
C10orf120
Chromosome 10 open reading frame 120.
      
 0.546
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
      
 0.541
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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