GET3 protein (Macaca fascicularis) - STRING interaction network

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GET3

ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)

Predicted Functional Partners:

GET4

0.976

BAG6

0.959

UBL4A

0.924

ENSMFAP00000005008

0.893

GET1

0.893

ENSMFAP00000009685

0.887

CAMLG

0.887

STX5

0.880

SGTB

0.865

RNF126

0.864

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG6	GET3	ENSMFAP00000003182	ENSMFAP00000001955	BCL2 associated athanogene 6.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.959
BAG6	GET4	ENSMFAP00000003182	ENSMFAP00000006457	BCL2 associated athanogene 6.	Guided entry of tail-anchored proteins factor 4.	0.987
BAG6	RNF126	ENSMFAP00000003182	ENSMFAP00000008209	BCL2 associated athanogene 6.	Ring finger protein 126.	0.929
BAG6	SGTB	ENSMFAP00000003182	ENSMFAP00000024405	BCL2 associated athanogene 6.	Small glutamine rich tetratricopeptide repeat containing beta.	0.846
BAG6	STX5	ENSMFAP00000003182	ENSMFAP00000034117	BCL2 associated athanogene 6.	Syntaxin 5; Belongs to the syntaxin family.	0.651
BAG6	UBL4A	ENSMFAP00000003182	ENSMFAP00000009313	BCL2 associated athanogene 6.	Ubiquitin like 4A.	0.975
CAMLG	ENSMFAP00000005008	ENSMFAP00000010134	ENSMFAP00000005008	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Uncharacterized protein.	0.828
CAMLG	GET1	ENSMFAP00000010134	ENSMFAP00000040387	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Guided entry of tail-anchored proteins factor 1.	0.828
CAMLG	GET3	ENSMFAP00000010134	ENSMFAP00000001955	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.887
CAMLG	GET4	ENSMFAP00000010134	ENSMFAP00000006457	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Guided entry of tail-anchored proteins factor 4.	0.534
CAMLG	UBL4A	ENSMFAP00000010134	ENSMFAP00000009313	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Ubiquitin like 4A.	0.438
ENSMFAP00000005008	CAMLG	ENSMFAP00000005008	ENSMFAP00000010134	Uncharacterized protein.	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	0.828
ENSMFAP00000005008	ENSMFAP00000009685	ENSMFAP00000005008	ENSMFAP00000009685	Uncharacterized protein.	Uncharacterized protein.	0.828
ENSMFAP00000005008	GET3	ENSMFAP00000005008	ENSMFAP00000001955	Uncharacterized protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.893
ENSMFAP00000005008	GET4	ENSMFAP00000005008	ENSMFAP00000006457	Uncharacterized protein.	Guided entry of tail-anchored proteins factor 4.	0.600
ENSMFAP00000005008	SGTB	ENSMFAP00000005008	ENSMFAP00000024405	Uncharacterized protein.	Small glutamine rich tetratricopeptide repeat containing beta.	0.468
ENSMFAP00000005008	STX5	ENSMFAP00000005008	ENSMFAP00000034117	Uncharacterized protein.	Syntaxin 5; Belongs to the syntaxin family.	0.471
ENSMFAP00000005008	UBL4A	ENSMFAP00000005008	ENSMFAP00000009313	Uncharacterized protein.	Ubiquitin like 4A.	0.608
ENSMFAP00000009685	ENSMFAP00000005008	ENSMFAP00000009685	ENSMFAP00000005008	Uncharacterized protein.	Uncharacterized protein.	0.828
ENSMFAP00000009685	GET1	ENSMFAP00000009685	ENSMFAP00000040387	Uncharacterized protein.	Guided entry of tail-anchored proteins factor 1.	0.828

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