node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | BDKRB2 | ENSMFAP00000010584 | ENSMFAP00000012628 | SERPIN domain-containing protein; Belongs to the serpin family. | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | 0.968 |
AGT | EDN1 | ENSMFAP00000010584 | ENSMFAP00000007622 | SERPIN domain-containing protein; Belongs to the serpin family. | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.712 |
AGT | EDN2 | ENSMFAP00000010584 | ENSMFAP00000002418 | SERPIN domain-containing protein; Belongs to the serpin family. | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family. | 0.438 |
AGT | EDN3 | ENSMFAP00000010584 | ENSMFAP00000043694 | SERPIN domain-containing protein; Belongs to the serpin family. | Endothelin 3. | 0.495 |
AGT | EDNRA | ENSMFAP00000010584 | ENSMFAP00000001958 | SERPIN domain-containing protein; Belongs to the serpin family. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.976 |
AGT | F2 | ENSMFAP00000010584 | ENSMFAP00000017755 | SERPIN domain-containing protein; Belongs to the serpin family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.675 |
AGT | GNA11 | ENSMFAP00000010584 | ENSMFAP00000041087 | SERPIN domain-containing protein; Belongs to the serpin family. | G protein subunit alpha 11. | 0.499 |
AGT | GNAQ | ENSMFAP00000010584 | ENSMFAP00000034906 | SERPIN domain-containing protein; Belongs to the serpin family. | G protein subunit alpha q. | 0.693 |
AGT | KNG1 | ENSMFAP00000010584 | ENSMFAP00000040815 | SERPIN domain-containing protein; Belongs to the serpin family. | Kininogen 1. | 0.694 |
BDKRB2 | AGT | ENSMFAP00000012628 | ENSMFAP00000010584 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | SERPIN domain-containing protein; Belongs to the serpin family. | 0.968 |
BDKRB2 | EDN1 | ENSMFAP00000012628 | ENSMFAP00000007622 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.947 |
BDKRB2 | EDN3 | ENSMFAP00000012628 | ENSMFAP00000043694 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Endothelin 3. | 0.461 |
BDKRB2 | EDNRA | ENSMFAP00000012628 | ENSMFAP00000001958 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.933 |
BDKRB2 | F2 | ENSMFAP00000012628 | ENSMFAP00000017755 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.940 |
BDKRB2 | GNA11 | ENSMFAP00000012628 | ENSMFAP00000041087 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha 11. | 0.936 |
BDKRB2 | GNAQ | ENSMFAP00000012628 | ENSMFAP00000034906 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha q. | 0.952 |
BDKRB2 | KNG1 | ENSMFAP00000012628 | ENSMFAP00000040815 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Kininogen 1. | 0.998 |
EDN1 | AGT | ENSMFAP00000007622 | ENSMFAP00000010584 | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | SERPIN domain-containing protein; Belongs to the serpin family. | 0.712 |
EDN1 | BDKRB2 | ENSMFAP00000007622 | ENSMFAP00000012628 | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | 0.947 |
EDN1 | EDN2 | ENSMFAP00000007622 | ENSMFAP00000002418 | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family. | 0.952 |