Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC22A7Solute carrier family 22 member 7. (548 aa)    
Predicted Functional Partners:
SLC22A8
Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Transports specifically estrone-3-sulfate (E1S), benzylpenicillin (PCG), methotrexate and estradiol-17-beta-glucuromide. Also transports 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), p- amino-hippurate (PAH) and indoxyl sulfate (IS). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
  
 
0.918
SLC10A2
Solute carrier family 10 member 2.
   
  
 0.701
ABCC6
ATP binding cassette subfamily C member 6.
   
 
 0.629
SLCO1A2
Solute carrier organic anion transporter family member.
   
  
 0.614
SLC16A6
Solute carrier family 16 member 6.
   
 
 0.605
ABCB1
Multidrug resistance p-glycoprotein.
   
 
 0.586
ABCC3
ATP binding cassette subfamily C member 3.
   
 
 0.579
SLC16A14
Solute carrier family 16 member 14.
    
 
 0.568
SLC22A1
Solute carrier family 22 member 1.
  
 
0.564
SLC19A3
Thiamine transporter 2; Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity). Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
    
 
 0.551
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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