Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMFAP00000002011Uncharacterized protein. (179 aa)    
Predicted Functional Partners:
IFNAR2
Uncharacterized protein.
    
 0.948
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.946
IRF7
Interferon regulatory factor 7.
    
 0.937
IRF3
Interferon regulatory factor 3.
    
 0.933
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.913
RELA
RELA proto-oncogene, NF-kB subunit.
     
 0.900
ISG15
ISG15 ubiquitin like modifier.
    
 0.883
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
    
   0.791
JAK2
Tyrosine-protein kinase.
    
 0.774
JAK1
Tyrosine-protein kinase.
    
 0.758
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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