Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102120931Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (65 aa)    
Predicted Functional Partners:
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
  
  
 0.843
LOC102121958
Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.829
LOC102122363
Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.
  
 
 0.713
LOC102119017
Uncharacterized protein.
     
 0.698
SPAG11B
Uncharacterized protein.
      
 0.635
ENSMFAP00000023199
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.611
DEFB108B
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.605
DEFB119
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.592
DEFB110
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
 
 0.548
C16orf90
Chromosome 16 open reading frame 90.
  
     0.498
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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