STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)    
Predicted Functional Partners:
CERS4
Ceramide synthase 4.
   
 0.965
UGCG
UDP-glucose ceramide glucosyltransferase.
   
 
 0.950
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.948
CERS2
Ceramide synthase 2.
   
 0.943
CERS1
TLC domain-containing protein.
   
 0.940
CERS6
Ceramide synthase 6.
   
 0.940
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.937
CERS3
Ceramide synthase 3.
   
 0.934
SGMS1
Sphingomyelin synthase 1.
   
 
 0.933
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
   
 
 0.931
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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