| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALPL | BGLAP | ENSMFAP00000006232 | ENSMFAP00000002148 | Alkaline phosphatase. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 0.709 |
| ALPL | BMP2 | ENSMFAP00000006232 | ENSMFAP00000025040 | Alkaline phosphatase. | Bone morphogenetic protein 2. | 0.546 |
| ALPL | IBSP | ENSMFAP00000006232 | ENSMFAP00000013470 | Alkaline phosphatase. | Integrin binding sialoprotein. | 0.566 |
| ALPL | PTH | ENSMFAP00000006232 | ENSMFAP00000019698 | Alkaline phosphatase. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). | 0.401 |
| ALPL | RUNX2 | ENSMFAP00000006232 | ENSMFAP00000035682 | Alkaline phosphatase. | RUNX family transcription factor 2. | 0.749 |
| ALPL | SOST | ENSMFAP00000006232 | ENSMFAP00000028397 | Alkaline phosphatase. | Sclerostin. | 0.489 |
| ALPL | SPP1 | ENSMFAP00000006232 | ENSMFAP00000037871 | Alkaline phosphatase. | Secreted phosphoprotein 1. | 0.558 |
| BGLAP | ALPL | ENSMFAP00000002148 | ENSMFAP00000006232 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Alkaline phosphatase. | 0.709 |
| BGLAP | BMP2 | ENSMFAP00000002148 | ENSMFAP00000025040 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Bone morphogenetic protein 2. | 0.711 |
| BGLAP | FURIN | ENSMFAP00000002148 | ENSMFAP00000007744 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.696 |
| BGLAP | GGCX | ENSMFAP00000002148 | ENSMFAP00000039615 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Gamma-glutamyl carboxylase. | 0.976 |
| BGLAP | IBSP | ENSMFAP00000002148 | ENSMFAP00000013470 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Integrin binding sialoprotein. | 0.712 |
| BGLAP | PCSK4 | ENSMFAP00000002148 | ENSMFAP00000046008 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. | 0.696 |
| BGLAP | PTH | ENSMFAP00000002148 | ENSMFAP00000019698 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). | 0.853 |
| BGLAP | RUNX2 | ENSMFAP00000002148 | ENSMFAP00000035682 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | RUNX family transcription factor 2. | 0.940 |
| BGLAP | SOST | ENSMFAP00000002148 | ENSMFAP00000028397 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Sclerostin. | 0.826 |
| BGLAP | SPP1 | ENSMFAP00000002148 | ENSMFAP00000037871 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | Secreted phosphoprotein 1. | 0.689 |
| BMP2 | ALPL | ENSMFAP00000025040 | ENSMFAP00000006232 | Bone morphogenetic protein 2. | Alkaline phosphatase. | 0.546 |
| BMP2 | BGLAP | ENSMFAP00000025040 | ENSMFAP00000002148 | Bone morphogenetic protein 2. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 0.711 |
| BMP2 | IBSP | ENSMFAP00000025040 | ENSMFAP00000013470 | Bone morphogenetic protein 2. | Integrin binding sialoprotein. | 0.488 |
