Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TYSND1Trypsin domain containing 1. (566 aa)    
Predicted Functional Partners:
LONP2
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.
   
 0.932
PEX5
Peroxisomal biogenesis factor 5.
    
 0.918
ACOX1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
    
 0.893
PEX14
Pex14_N domain-containing protein.
     
 0.860
PEX10
Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes.
     
 0.831
ACAA1
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.824
GNPAT
Dihydroxyacetone phosphate acyltransferase.
   
 
 0.817
PEX5L
Peroxisomal biogenesis factor 5 like.
    
 0.808
PEX12
Pex2_Pex12 domain-containing protein.
     
 0.790
ACOT8
Acyl-CoA thioesterase 8.
   
 
 0.783
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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