| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC37 | LRRK2 | ENSMFAP00000006602 | ENSMFAP00000002248 | Cell division cycle 37. | Leucine rich repeat kinase 2. | 0.917 |
| CDC37 | MAPT | ENSMFAP00000006602 | ENSMFAP00000034395 | Cell division cycle 37. | Microtubule-associated protein. | 0.612 |
| CDC37 | STUB1 | ENSMFAP00000006602 | ENSMFAP00000029975 | Cell division cycle 37. | STIP1 homology and U-box containing protein 1. | 0.681 |
| DNM1L | LRRK2 | ENSMFAP00000010214 | ENSMFAP00000002248 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Leucine rich repeat kinase 2. | 0.924 |
| LRRK2 | CDC37 | ENSMFAP00000002248 | ENSMFAP00000006602 | Leucine rich repeat kinase 2. | Cell division cycle 37. | 0.917 |
| LRRK2 | DNM1L | ENSMFAP00000002248 | ENSMFAP00000010214 | Leucine rich repeat kinase 2. | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.924 |
| LRRK2 | MAPT | ENSMFAP00000002248 | ENSMFAP00000034395 | Leucine rich repeat kinase 2. | Microtubule-associated protein. | 0.893 |
| LRRK2 | MBP | ENSMFAP00000002248 | ENSMFAP00000029701 | Leucine rich repeat kinase 2. | Myelin basic protein. | 0.909 |
| LRRK2 | MSN | ENSMFAP00000002248 | ENSMFAP00000034763 | Leucine rich repeat kinase 2. | Moesin. | 0.915 |
| LRRK2 | RAB29 | ENSMFAP00000002248 | ENSMFAP00000041746 | Leucine rich repeat kinase 2. | RAB29, member RAS oncogene family. | 0.906 |
| LRRK2 | SNCA | ENSMFAP00000002248 | ENSMFAP00000041319 | Leucine rich repeat kinase 2. | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | 0.906 |
| LRRK2 | STUB1 | ENSMFAP00000002248 | ENSMFAP00000029975 | Leucine rich repeat kinase 2. | STIP1 homology and U-box containing protein 1. | 0.918 |
| LRRK2 | YWHAB | ENSMFAP00000002248 | ENSMFAP00000023144 | Leucine rich repeat kinase 2. | 14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] | 0.882 |
| LRRK2 | YWHAG | ENSMFAP00000002248 | ENSMFAP00000038430 | Leucine rich repeat kinase 2. | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. | 0.881 |
| MAPT | CDC37 | ENSMFAP00000034395 | ENSMFAP00000006602 | Microtubule-associated protein. | Cell division cycle 37. | 0.612 |
| MAPT | LRRK2 | ENSMFAP00000034395 | ENSMFAP00000002248 | Microtubule-associated protein. | Leucine rich repeat kinase 2. | 0.893 |
| MAPT | MBP | ENSMFAP00000034395 | ENSMFAP00000029701 | Microtubule-associated protein. | Myelin basic protein. | 0.472 |
| MAPT | MSN | ENSMFAP00000034395 | ENSMFAP00000034763 | Microtubule-associated protein. | Moesin. | 0.413 |
| MAPT | SNCA | ENSMFAP00000034395 | ENSMFAP00000041319 | Microtubule-associated protein. | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | 0.981 |
| MAPT | STUB1 | ENSMFAP00000034395 | ENSMFAP00000029975 | Microtubule-associated protein. | STIP1 homology and U-box containing protein 1. | 0.916 |
