Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)    
Predicted Functional Partners:
NCK2
Cytoplasmic protein.
    
 
 0.610
CBLB
Cbl proto-oncogene B.
    
   0.571
COL1A1
Collagen type I alpha 1 chain.
   
 
 0.565
PAWR
Pro-apoptotic WT1 regulator.
      
 0.564
COL3A1
Collagen type III alpha 1 chain.
   
 
 0.564
COL5A1
Collagen type V alpha 1 chain.
   
 
 0.561
GNE
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.
      
 0.549
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1.
      
 0.547
UHMK1
U2AF homology motif kinase 1.
      
 0.537
KANK3
KN motif and ankyrin repeat domains 3.
   
  
 0.511
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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