STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.997
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.986
DDB2
Damage specific DNA binding protein 2.
    
0.972
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.971
COP1
COP1 E3 ubiquitin ligase.
    
  0.955
UVSSA
UV stimulated scaffold protein A.
    
 
 0.947
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.933
POLR2I
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
 0.915
RBX1
RING-box protein 1.
    
 0.913
ENSMFAP00000045746
Zf-rbx1 domain-containing protein.
    
 0.913
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.