STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP21Matrix metallopeptidase 21. (567 aa)    
Predicted Functional Partners:
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.710
TIMP3
Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15 (By similarity).
   
 0.626
CCDC63
Coiled-coil domain containing 63.
      
 0.613
SPAG1
Sperm associated antigen 1.
      
 0.608
DNAH7
Dynein axonemal heavy chain 7.
      
 0.535
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.532
CDK13
Cyclin dependent kinase 13.
   
  
 0.494
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 0.491
NID2
Nidogen 2.
     
 0.487
NID1
Nidogen 1.
     
 0.487
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.