Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (529 aa)    
Predicted Functional Partners:
MAML1
Mastermind like transcriptional coactivator 1.
   
 0.999
NOTCH1
Notch receptor 1.
   
 0.999
NOTCH2
Notch receptor 2.
    
 0.998
MAML2
Mastermind like transcriptional coactivator 2.
   
 0.998
NOTCH4
Notch receptor 4.
    
 0.998
NOTCH3
Notch receptor 3.
    
 0.997
SPEN
Spen family transcriptional repressor.
    
 0.993
SNW1
SNW domain containing 1.
   
 0.990
NCOR2
Nuclear receptor corepressor 2.
    
 0.990
CREBBP
CREB binding protein.
    
 0.986
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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