node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIAO1 | CIAO2B | ENSMFAP00000017222 | ENSMFAP00000004222 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 2B. | 0.997 |
CIAO1 | CIAO3 | ENSMFAP00000017222 | ENSMFAP00000040683 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. | 0.895 |
CIAO1 | ERCC2 | ENSMFAP00000017222 | ENSMFAP00000037945 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.875 |
CIAO1 | FBXL5 | ENSMFAP00000017222 | ENSMFAP00000023352 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | F-box and leucine rich repeat protein 5. | 0.697 |
CIAO1 | MMS19 | ENSMFAP00000017222 | ENSMFAP00000026800 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.991 |
CIAO1 | NARF | ENSMFAP00000017222 | ENSMFAP00000033425 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.811 |
CIAO1 | NDOR1 | ENSMFAP00000017222 | ENSMFAP00000044140 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.520 |
CIAO1 | NUBP1 | ENSMFAP00000017222 | ENSMFAP00000045440 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.661 |
CIAO1 | SLC25A5 | ENSMFAP00000017222 | ENSMFAP00000007280 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.498 |
CIAO1 | STEAP2 | ENSMFAP00000017222 | ENSMFAP00000028144 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | STEAP2 metalloreductase. | 0.404 |
CIAO2B | CIAO1 | ENSMFAP00000004222 | ENSMFAP00000017222 | Cytosolic iron-sulfur assembly component 2B. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | 0.997 |
CIAO2B | CIAO3 | ENSMFAP00000004222 | ENSMFAP00000040683 | Cytosolic iron-sulfur assembly component 2B. | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. | 0.860 |
CIAO2B | ERCC2 | ENSMFAP00000004222 | ENSMFAP00000037945 | Cytosolic iron-sulfur assembly component 2B. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.922 |
CIAO2B | FBXL5 | ENSMFAP00000004222 | ENSMFAP00000023352 | Cytosolic iron-sulfur assembly component 2B. | F-box and leucine rich repeat protein 5. | 0.821 |
CIAO2B | MMS19 | ENSMFAP00000004222 | ENSMFAP00000026800 | Cytosolic iron-sulfur assembly component 2B. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.995 |
CIAO2B | NARF | ENSMFAP00000004222 | ENSMFAP00000033425 | Cytosolic iron-sulfur assembly component 2B. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.791 |
CIAO2B | NDOR1 | ENSMFAP00000004222 | ENSMFAP00000044140 | Cytosolic iron-sulfur assembly component 2B. | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.612 |
CIAO2B | NUBP1 | ENSMFAP00000004222 | ENSMFAP00000045440 | Cytosolic iron-sulfur assembly component 2B. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.536 |
CIAO2B | SLC25A5 | ENSMFAP00000004222 | ENSMFAP00000007280 | Cytosolic iron-sulfur assembly component 2B. | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.527 |
CIAO2B | STEAP2 | ENSMFAP00000004222 | ENSMFAP00000028144 | Cytosolic iron-sulfur assembly component 2B. | STEAP2 metalloreductase. | 0.614 |